Prostate-specific antigen (PSA) is a glycoprotein with a molecular weight of about 32 000 Da, that consists of one polypeptide chain. In the serum the PSA contains in two forms. It is the free form and connected with various fibers of blood. The main part of the serum PSA is a complex with α1- antichymothrypsine (PSA-ACT). But there is a great difference in free PSA/PSA-ACT ratio in different groups of patients. In the case of benign hyperplasia the part of free PSA is higher than in the case of prostate cancer.
OncoEIA-free PSA kit is intended for the quantitative determination of free fraction of the prostate-specific antigen in human serum.