Alkor Bio, Ltd.

Fetal damage is now thought to be mainly due to primary infection, rather than to a re-infection. CMV is also an important cause of complications in organ transplantation, particularly in kidney transplantation. Again in these cases, primary infection is more harmful than a re-infection. 

The diagnosis of recently acquired primary infection by means of specifi c IgM antibodies can be difficult, due to the IgM presence even in recurring infections. In addition, circulating IgM antibodies may persist for a lot of months and even for two years in immunodepressed subjects. Measuring the avidity of specifi c IgG was demonstrated to be particularly useful in identifying primary infection. As a matter of fact, the initial IgG antibody response to infection is characterized by antibodies with low avidity, in which binding to the specifi c antigen sites is easily dissociated. 

Cytomegalovirus IgG Avidity kit is designed for detection of IgG antibodies avidity for Cytomegalovirus in human serum or plasma by enzyme immunoassay method - EIA (Sandwich assay).