Alkor Bio, Ltd.

Surface antigen (HBsAg) is a glycosylated envelope protein of HBV and is an important marker of infection. HBsAg contains a determinant «a» is common to all subtypes and additional subdeterminanty (d and y), causing differences in immunologic subgroups (ad and ay). 

HBsAg as the main serological marker of hepatitis B virus plays a key role in the diagnosis and study of the etiology, pathogenesis, clinical and prevention of this infection. Thus, in establishing the etiologic diagnosis of hepatitis B HBsAg may be the first marker of infection and serve as one of the main indicators for the diagnosis (Fig. 1). Detection of HBsAg in patients with chronic hepatitis and cirrhosis of the liver shows the etiology of the disease (Fig. 2). Identification HBsAg population demonstrated the presence of asymptomatic carriers of HBsAg, has established its role as the main reservoir of infection, defined risk groups. In the service of blood transfusion exclusion of persons with the presence of HBsAg from donation resulted in a significant reduction in post-transfusion hepatitis. Blood samples from the presence of HBsAg should not be used for transfusion or for production of these blood products. 

In terms of clinical practice seems appropriate quantification of HBsAg in the blood, as this information will help to correct diagnosis and adequate treatment to choose to follow the dynamics of infectious the process. 

The purpose of this reagent kit is a qualitative or quantitative determination of serum surface antigen (HBsAg) of hepatitis B virus.